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July 25, 2011

Today’s Top Anti Aging Drugs

Today's Top Anti Aging Drugs

Top Anti Aging Drugs

Hormones currently top the list as being the most effective drugs to manage the symptoms of aging.  But, there are several nutritional supplements that can slow aging and potentially reverse aging to some degree, at least at the cellular level.   Together hormones and supplements are today’s top anti aging drugs.

Don’t simply rely on a doctor’s prescription pad to control aging, though.  If you really want to manage the aging process well you are going to need to take some action on your own through better nutrition and exercise.

Hormones: the Best Anti Aging Drugs

Sex hormone replacement is currently the best way to manage many of the symptoms of aging.  Hormone replacement in men mainly consists of testosterone replacement, and in women it can mean replacing estrogens, progesterone, and testosterone.

Hormone replacement is very effective in treating women suffering from menopausal symptoms like hot flashes, night sweats, foggy thinking, anxiety, depression, and decreased energy to mention just a few.

Testosterone is the “hormone of desire” in both men and women and can improve libido and sexual performance.  Testosterone is extremely vital for maintaining muscle mass and strength, which improves quality of life and improves metabolism making weight control easier.  Testosterone also has many heart and brain benefits. See “Testosterone – Not Just For Your Libido”.

Testosterone, estrogens, and progesterone all have beneficial effects on bone density, too.  Osteoporosis is a huge problem.  Unfortunately, its significance isn’t always fully appreciated and it remains under diagnosed and under treated.  Maintaining healthy hormone levels is the best way to maintain healthy bones.

More and more we are hearing about adverse effects of the bisphosphonate drugs, the most common drugs, that are prescribed for osteoporosis. Hormone replacement is a more physiologic way to address declining bone density than the bisphosphonates and is associated with fewer side effects.

Growth hormone can reverse some of the physical signs of aging.  In adults it is largely a healing hormone.  Growth hormone replacement improves hair and skin growth, lung function, memory and cognitive skills, muscle strength, sleep, wound healing, and decreases body fat.

Controversy surrounding the best way to diagnosis adult growth hormone deficiency and uncertainty regarding interpretation of the law have deterred some physicians from prescribing human growth hormone for legitimate medical reasons, though.

Low thyroid frequently occurs with aging.  There tends to be an over reliance on using laboratory tests alone to make the diagnosis of low thyroid, rather than taking into account a patient’s symptoms.  Thyroid is the main regulator of metabolism.  It makes virtually every process in the body work better.  When thyroid is low the many physiologic processes in the body all slow down.

Nutritional Supplements

Let’s take a look at four nutritional supplements – resveratrol, TA-65, vitamin D and fish oil (omega-3 fatty acids) that may address aging at the cellular level.


Calorie restriction has been shown to increase longevity through changes in metabolic mechanisms.  Resveratrol stimulate sirtuin genes that ultimately lead to changes in these same metabolic mechanisms.  


TA-65 activates telomerase, a naturally occurring enzyme that lengthens telomeres.  Telomeres are caps of DNA at both ends of chromosomes. Telomeres shorten each time a cell divides.  When telomeres get too short the cell dies or becomes non-functional.  Longer telomeres are associated with increased longevity.  In non-germ cells telomerase is in its default state where it is turned off.  TA-65 turns telomerase on enabling it to repair shortened telomeres.  See “TA-65: A Revolutionary Anti Aging Supplement”.

Fish Oil and Vitamin D

Many are already aware of the health benefits of fish oil (and other omega-3 fatty acids) and vitamin D.  What may not be known to many is that both fish oil and vitamin D can slow telomere shortening.  In addition, fish oil is a natural anti-inflammatory.  Inflammation is linked to heart disease, cancer, stroke, diabetes, and many other chronic diseases.

High vitamin D levels can cut the risk of cancer and may protect against neuro-degenerative diseases like Parkinson’s disease.  Low vitamin D is also linked to diabetes.  See “In The News For April 11: Are You Vitamin D Deficient“.

Consider these top anti aging drugs and supplements to get the most out of life.

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Dr. Joe Jacko

Dr. Joe is board certified in internal medicine and sports medicine with additional training in hormone replacement therapy and regenerative medicine. He has trained or practiced at leading institutions including the Hughston Clinic, Cooper Clinic, Steadman-Hawkins Clinic of the Carolinas, and Cenegenics. He currently practices in Columbus, Ohio at Grandview Primary Care. Read more about Dr. Joe Jacko

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