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Dr. Joe Jacko
Pentosan Polysulfate Sodium for Osteoarthritis Pentosan polysulfate sodium is a repurposed drug for osteoarthritis may provide hope and relief who suffer from the pain and disability related to osteoarthritis. Â Osteoarthritis is sometimes referred to as “wear and tear” arthritis distinguishing it from inflammatory arthritis like rheumatoid arthritis and its cousins. Osteoarthritis by the Numbers Osteoarthritis
Dr. Joe Jacko
Can we really live to be 100 years old, and be in good health? Is 100 realistically the new 30? Our life expectancy is about twice that of our hunter-gatherer ancestors but has remained relatively flat since 2014 despite an accelerating rate of medical advancements. Â This raises the question then about how just important are
Dr. Joe Jacko
Risk of Cognitive Decline from Hearing Loss When someone asks, “Can you hear me now?” You want to able to say “yes”. Having age related hearing loss puts you at risk for cognitive decline. Â As you likely know, cognitive decline is challenging to treat so you certainly want to minimize any risk you can. Cognitive
Dr. Joe Jacko
Gratitude Improves Longevity in Older Women We have written a few posts over the years on the importance of gratitude and its effects on health. Those articles are usually published around Thanksgiving and have been focused on the relationship between gratitude and happiness and improvement in health. But this recent article published in JAMA Psychiatry addresses
Dr. Joe Jacko
Does Medicine Make a Difference or Impact? Does medicine make a difference? We all know the person who spends every waking moment focused on staying healthy; making sure they eat well, get the right kind of exercise, get proper sleep, avoid unhealthy habits, keep unhealthy stress to minimum, follow all the recommend guidelines for preventive
Dr. Joe Jacko
The FDA Drug Approval Process It helps to understand the drug approval process. First, it is very expensive to bring a drug to market ranging from $1 billion to $2.6 billion dollars per drug and pharmaceutical companies have more losers than they do winners. Secondly, the drug approval process is lengthy and takes years. First,
Dr. Joe Jacko
Plant-Based Diet is Better for Men A recent study published in Cancer found that men with prostate cancer who ate a plant-based diet had higher quality of life than those who consumed more meat in their diets.  The study involved 3,505 men who had non-metastatic prostate cancer. Men in the study filled out a diet questionnaire every
Dr. Joe Jacko
The Alliance for Longevity Initiatives The Alliance for Longevity Initiatives was founded in 2022 and advocates for policies and initiatives that extend human healthspan by ending the harm of age related diseases like Alzheimer’s, cardiovascular disease, and cancer. Â It also promotes biomedical technology with aims to increase its accessibility to the general public. Longevity Science
Dr. Joe Jacko
What is Vacation Deficit Disorder Feeling down in the dumps and depressed? Â If so, you may be suffering from vacation deficit disorder. Vacation deficit disorder is not a recognizable medical condition, yet is defined as “Americans who think that annual vacation is important, but who are not confident that they will take
Dr. Joe Jacko
Early Onset Dementia Early onset dementia has been on the rise and researchers have now identified 15 risk factors for this progressive neurodegenerative disease. Early onset dementia is described as dementia striking before age 65. Dementia is devastating but especially when the onset strikes at earlier ages to people who are still working, are leading
Dr. Joe Jacko
Artificial Sweeteners Change the Gut Microbiome Don’t let the use of artificial sweeteners change your gut microbiome. In our post Gut Microbiome: How it Keeps You Healthy we discussed the importance of the gut microbiome. One hundred trillion microorganisms comprise the gut microbiome. The gut microbiome plays a huge role in our immune system. The gut
Dr. Joe Jacko
Get Healthy During the Holidays What better time get healthy and start healthy lifestyle habits than the holidays? What? You’re kidding me? No, I am not. The holidays can be a great time to turn you health around and get healthy. Many people have time off during the holidays and that means more time to
Dr. Joe Jacko
Smart Gym Equipment How would you like to obtain better health and fitness results in less time? Believe it or not, with smart gym equipment, that is now possible. Technology including AI is taking exercise to a different stratosphere enabling exercisers to get a better health and fitness return on their exercise time. And, who
Dr. Joe Jacko
What is Biohacking? If you stay current on health and fitness news you likely have heard the word “biohacking”, and while you may have a vague sense of what it refers to, you may still have some confusion over the term. Today we will try to clarify what biohacking is and describe the various forms
Dr. Joe Jacko
Aging is Exponential, Not Linear Aging is a complex phenomenon. Because we get a year older each year we tend to think that we age biologically one year at a time. We think biological aging is linear, but it is not. It is exponential. We don’t perceive much of change in our health and how
Dr. Joe Jacko
Protect Yourself Against COVID with Exercise A recent review published in Current Sports Medicine Reports suggests that exercise may be the most important “medicine” for COVID 19. This should not be too surprising given everything we know about the positive effects exercise has on the immune system and cardiovascular and neurologic health. Vaccinations and boosters,
Dr. Joe Jacko
Removing Senescent or Zombie Cells with Senolytics What are senescent cells and what are senolytics? Let’s first start with discussing what senescent cells are. Senescent cells are cells that no longer divide (though some may be able to be “rehabilitated” to once again divide) and are non-functional. Cellular senescence is one of the 12 hallmarks
Dr. Joe Jacko
Longevity Benefits of Metformin What if I told you that there is an inexpensive FDA approved drug that has been used for over 70 years and it has an excellent safety record, and it shows promise great promise in improving longevity? Would you be interested in learning more about it? I suspect so, which is
Dr. Joe Jacko
Life Extension Benefits of Rapamycin Do you want to live longer healthier? Is so, then rapmycin is something you will want to know. Rapamycin is the hot topic in the life extension or longevity arena. Rapamycin has been shown to increases median life expectancy up to 60% in animal models. That is impressive and human
Dr. Joe Jacko
Why We Fall? Have you wondered why we fall especially as we get older? And, can anything be done to prevent them? Falls are a bigger problem than many believe and do not receive the attention they should. Many conditions contribute to falling. These are called risk factors. The good news is that many of
Dr. Joe Jacko
How Many Daily Steps Needed to Improve Health? Most of us have heard that you need to take 10,000 daily steps a day to improve health. Actually, a new study shows that you can still improve health with as few as 4,000 daily steps 93,867 steps to be precise), but 10,000 daily steps gives you
Dr. Joe Jacko
Reduce Post-Op Complications with Exercise You can reduce post-op complications with as little as 4 to 6 weeks of high intensity training prior to surgery. And, that is true even if you are not currently exercising. The reductions on post-op surgical complications is significant following a period of high intensity interval training in the weeks
Dr. Joe Jacko
Water is the most important nutrient. Along with carbohydrates, fats, and protein, water is considered a macronutrient – something the body needs in large amounts. And, this is even more important when it comes to athletic performance. As little as 1% reduction in body water content is enough to hamper athletic performance – maybe as
Dr. Joe Jacko
What is Sprint Interval Training? Believe it or not, but you can SIT and improve your health and fitness. SIT refers to sprint interval training which is similar to or HIIT or high intensity interval training with one significant difference. I know we have written articles that describing sitting as the new smoking in the
Dr. Joe Jacko
Why Keeping Weight Off is Difficult Have you wondered why keeping weight off is difficult once you have lost it? This post will look at some of the reasons why keeping weight off is challenging. There is perhaps nothing more frustrating than working really hard to lose weight, only to regain it later. Before we
Dr. Joe Jacko
Craving Calorie-Dense Foods? Could Be Stress Are you craving calorie-dense foods? It could be related to stress. Researchers from Garvan Institute of Medical Research in Australia found that stress overrides that part of the brain that signals satiety or the sense of feeling full. Chronic stress sparks alterations of brain activity that boost cravings for
Dr. Joe Jacko
Does Taurine in Energy Drinks Slow Aging? We have a great news – especially if you are a mouse, worm, or monkey. It appears that taurine, an amino acid, found in many energy drinks slows aging in these organisms. Might is slow aging in humans? What is Taurine? Taurine is unique among amino acids in
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