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Dr. Joe Jacko
Fasting or Daily Calorie Restriction? Should you fast or practice daily calorie restriction to lose more weight and improve your blood pressure, blood sugar, and cholesterol? A study published in the Annals of Internal Medicine on April 1, 2025, found that participants who practiced intermittent fasting three non-consecutive days of the week lost more weight
Dr. Joe Jacko
More Flu in Those Who Got the Flu Vaccine The Cleveland Clinic published a pre-print study showing that its employees who received the flu vaccine for the 2024-25 flu season were 27% more likely to get the flu compared to employees not vaccinated. The Cleveland Clinic mandates the flu shot but allows for medical and
Dr. Joe Jacko
Exercise Improves Brain Insulin Signaling We now have the first study showing that exercise improves brain insulin signaling. That exercise improves insulin sensitivity in muscle cells has long been known, but we now know something similar happens in the brain with exercise. Why is this important? We know that exercise improves brain function. Now we have
Dr. Joe Jacko
VAERS U.S. COVID-19 Vaccine Data Today, we will share U.S. COVID-19 vaccine data from the VAERS database. Recently, we shared data from the Public Health Agency of Canada, which shows higher COVID-19 deaths among those who were vaccinated for COVID-19, with death rates proportional to the number of boosters received. VAERS is an acronym for
Dr. Joe Jacko
Nostalgia Enhances Social Networks Nostalgia enhances social networks. Why is that important? Having strong social networks is a key contributor to good health and longevity. We discussed the importance of relationships and social networks in The Blue Zones: Create One for Yourself and SuperCentenarians: Living 110 Plus Years. This study found that nostalgia enhances social networks. Before we
Dr. Joe Jacko
Canadian COVID-19 Death Rates Following Vaccination Are COVID-19 death rates higher among those vaccinated? Â Despite being FDA-approved, there is increasing concern that the COVID-19 mRNA vaccines are not nearly as safe and effective as we have all been led to believe. Â Today, I am going to share data from the Public Health Agency of Canada
Dr. Joe Jacko
Did You Create Memories Today? Did you create memories today? Years ago, in the early to mid 1990’s I met a gentleman who had an extremely successful Amway business. Through his front yard, he would move nearly as much product in a month as a single Walmart. He said, “I used to spend money buying
Dr. Joe Jacko
Is mTOR a Key to Longevity? Is mTOR a key to longevity? Many scientists think mTOR may be the key to living longer and better. mTOR is a naturally occurring protein.  We have written about mTOR and the effect that rapamycin has on this protein in Incredible Life Extension Benefits of Rapamycin. Today, we are
Dr. Joe Jacko
Microplastics in the Body Should we fear microplastics in the body? Â Many think we should. Microplastics are nearly everywhere, and levels of microplastics in the brain have increased 50% from 2016 to 2024. Â Could these microplastics be a factor in dementia and other neurodegenerative conditions? The brain is not the only organ where we see
Dr. Joe Jacko
Slow Biological Aging by Volunteering You can slow biological aging with as little as one to four hours of volunteering a week according to this study published in Social Science & Medicine. This finding may not be surprising. Volunteering is a cornerstone of one of the Blue Zones inhabited by the Seventh Day Adventists in
Dr. Joe Jacko
Fat and Fit Better than Skinny and Unfit You want to live longer, right? Â To achieve that, are you better off being fat and fit, or better off being skinny but unfit? The title of the article probably provides the answer.. Fitness trumps fat. Fitness is far more important than the medical profession appreciates or
Dr. Joe Jacko
Insulin resistance is at the root of many chronic medical conditions and it is completely avoidable. So consider adding avoiding insulin resistance to your health New Year resolutions. Insulin resistance affects every organ system in the body. What is Insulin Resistance? Insulin is a hormone produced in the pancreas and released in response to meals.
Dr. Joe Jacko
Benefits of Short Bursts of Vigorous Activity If you don’t like to exercise then this article is for you. You should consider short bursts of vigorous activity. Here’s good news for middle-aged women who do not exercise. Â A study published in the British Sports Medical Journal reports that just 1.5 to 4 minutes of short
Dr. Joe Jacko
Heart Disease Related to Number of Push-Ups The number of push-ups you can perform correlates well with your risk of heart disease. Â Heart disease remains the number one killer in the United States despite our attempts to address risk factors like hypertension, elevated cholesterol, diabetes, and smoking. Several studies have suggested that physical activity provided
Dr. Joe Jacko
Lose Dose Naltrexone for Chronic Pain Low-dose naltrexone can be a very effective treatment for sufferers of chronic pain. And if you live long enough, you will likely have some degree of chronic pain. In recent years I have had much success using low-dose naltrexone in my patients who suffer from chronic pain. These patients
Dr. Joe Jacko
Pentosan Polysulfate Sodium for Osteoarthritis Pentosan polysulfate sodium is a repurposed drug for osteoarthritis which may provide hope and relief for those who suffer from pain and disability related to osteoarthritis. Â Osteoarthritis is sometimes referred to as “wear and tear” arthritis distinguishing it from inflammatory arthritis like rheumatoid arthritis and its cousins. Osteoarthritis by the
Dr. Joe Jacko
Can we live to be 100 years old, and be in good health? Is 100 realistically the new 30? Our life expectancy is about twice that of our hunter-gatherer ancestors but it has remained relatively flat since 2014 despite an accelerating rate of medical advancements. Â This raises the question then about how just important are
Dr. Joe Jacko
Risk of Cognitive Decline from Hearing Loss When someone asks, “Can you hear me now?” You want to be able to say “yes”. Having age-related hearing loss puts you at risk for cognitive decline. Â As you likely know, cognitive decline is challenging to treat so you certainly want to minimize any risk you can. Cognitive
Dr. Joe Jacko
Gratitude Improves Longevity in Older Women We have written a few posts over the years on the importance of gratitude and its effects on health. Those articles are usually published around Thanksgiving and have been focused on the relationship between gratitude and happiness and improvement in health. However, this recent article published in JAMA Psychiatry addresses
Dr. Joe Jacko
Does Medicine Make a Difference or Impact? Does medicine make a difference? We all know the person who spends every waking moment focused on staying healthy; making sure they eat well, get the right kind of exercise, get proper sleep, avoid unhealthy habits, keep unhealthy stress to a minimum, follow all the recommended guidelines for
Dr. Joe Jacko
The FDA Drug Approval Process It helps to understand the drug approval process. First, it is very expensive to bring a drug to market ranging from $1 billion to 2.6 billion dollars per drug, and pharmaceutical companies have more losers than they do winners. Secondly, the drug approval process is lengthy and takes years. First,
Dr. Joe Jacko
Plant-Based Diet is Better for Men A recent study published in Cancer found that men with prostate cancer who ate a plant-based diet had a higher quality of life than those who consumed more meat in their diets.  The study involved 3,505 men who had non-metastatic prostate cancer. Men in the study filled out a diet questionnaire
Dr. Joe Jacko
The Alliance for Longevity Initiatives The Alliance for Longevity Initiatives was founded in 2022 and advocates for policies and initiatives that extend human health span by ending the harm of age-related diseases like Alzheimer’s, cardiovascular disease, and cancer. Â It also promotes biomedical technology with the aims to increase its accessibility to the general public. Longevity
Dr. Joe Jacko
What is Vacation Deficit Disorder Feeling down in the dumps and depressed? Â If so, you may be suffering from vacation deficit disorder. Vacation deficit disorder is not a recognizable medical condition, yet is defined as “Americans who think that annual vacation is important, but who are not confident that they will take
Dr. Joe Jacko
Early Onset Dementia Early onset dementia has been on the rise and researchers have now identified 15 risk factors for this progressive neurodegenerative disease. Early onset dementia is described as dementia striking before age 65. Dementia is devastating especially when the onset strikes at earlier ages to people who are still working, are leading an
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