February 7, 2020

What is LGD 4033?

What is LGD 4033
Photo by Cristian Baron on Unsplash

So What is LGD 4033?

If you follow the body building blogs you may be asking yourself “what is LGD 4033”? LGD 4033 or ligandrol is a peptide and one of the more potent selective androgen receptor modulators (SARM). In a nutshell, it provides many of the same non-sexual benefits as testosterone without many of the side effects associated with testosterone replacement or use anabolic steroids.

In our previous post, we discussed the use of peptides. Today we are focusing on the use of LGD 4033.

If it builds muscle, you can probably guess that there is a good chance LGD 4033 is being used by body builders and anyone else interested in improving muscle strength and you would be right. Its use is banned, however, by many professional sports organizations as a performance enhancing agent.

But, LGD 4033 has potential legitimate medical uses in that it may prevent the muscle wasting that occurs with aging and from catabolic (muscle breakdown) diseases like AIDs, cancer, and other chronic disease like renal failure.

What Does LGD 4033 Do?

LGD 4033 is well tolerated and stimulates the androgen receptors on muscles and bones. Its biggest benefit is in improving muscle strength and mass improving body composition in the process.

It works rather quickly with most people seeing results as early as a week.

LGD 4033 can negatively alter cholesterol profile by lowering HDL or good cholesterol and raising triglycerides both of which are undesirable.

If taken for prolong periods, LGD 4033 can suppress natural testosterone production which returns to normal once LGD 4033 is discontinued.

What Does LGD 4033 Not Do?

It’s important to know what LGD 4033 does not do. Some of the side effects that come with testosterone replacement or anabolic steroids are minimized with LGD 4033. It does not cause gynecomastia (breast enlargement) that can occur with use of anabolic steroids as it does not raise estrogen levels.

It does not stimulate growth of the prostate like testosterone and anabolic steroids can. Hair loss, though still possible, is minimized with LGD 4033 compared to testosterone and anabolic steroids.

Unlike testosterone, LGD 4033 will not improve sexual health like libido and erectile function.

Where Can LGD 4033 Be Found?

LGD 4033 can be purchased online but to ensure you are getting true LGD 4033 we recommend going through a physician who can provide a prescription. At this time you would need to go through a compounding pharmacy to obtain LGD 4033.

While body builders take up to 10 mg of LGD 4033 daily (they usually take it in cycles), research studies using LGD 4033 have use doses of 0.1 mg, 0.3 mg, and 1 mg. Remember just because a little is good does not mean a lot is better.

When others ask you “What is LGD 4033?” You now know the answers. 

We will share more information as more research is done on this promising peptide.


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Dr. Joe Jacko

Dr. Joe is board certified in internal medicine and sports medicine with additional training in hormone replacement therapy and regenerative medicine. He has trained or practiced at leading institutions including the Hughston Clinic, Cooper Clinic, Steadman-Hawkins Clinic of the Carolinas, and Cenegenics. He currently practices in Columbus, Ohio at Grandview Primary Care. Read more about Dr. Joe Jacko

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